Currently there are "9 comments" on this Question:

  1. Kiara says:

    Sudafed and Benadryl have the same active ingredients, so no, you should not take them together.

    • MC says:

      “Sudafed and Benadryl have the same active ingredients, so no, you should not take them together.”

      Uh no, half-wit, they don’t. They aren’t even in the same class of medicatios. But thanks to the Internet, morons like you can practice medicine without a license.

  2. Zandra says:

    They are all fine together except the benadryl and zyrtec. Suddafed or pseudoephedrine is a oral decongestant that acts by constricting the blood vessels in your sinuses reducing inflammationSingular or montelukast is a leukotriene antagonist, meaning it blocks the action of leukotrienes which are a chemical released by some types of white blood cells when they detect an allergen.Zyrtec is a second generation antihistamine and benadryl is a first generation antihistamine. The only real difference is that benadryl is much more likely to get you drowsy, but it also is generally considered to be a more potent antihistamine. Taking both together isnt going to provide much if any benefit over just taking one of them and increases your risk of side effects.

  3. Emma says:

    Is it ok to take benadryl and sudafed? at the same time? one side of my nose hurts and I’m not sure if its allergies is clogged and my ear or a cold, is it ok if I take both b

  4. Jene says:

    You might need a nap.  But Wellbutrin tends to increase energy while Benadryl causes drowsiness, so they might cancel each other out.  As a Wellbutrin user, I find that taking a 24 hour allergy medication before bed is sufficient. More:http://wiki.answers.com/Q/What_happens_if_you_take_Benadryl_and_Wellbutrin_together

  5. Maurita says:

    Taking Benadryl, Sudafed and Nyquil at the same time may case intoxication and drowsiness. More:http://www.chacha.com/question/what-would-happen-if-you-took-benadryl-with-sudafed-and-nyquil

  6. Sudie says:

    Nothing adverse… Tylenol PM is Tylenol and Benadryl together. More:http://wiki.answers.com/Q/What_happens_when_you_take_Tylenol_and_Benadryl_together

  7. Sau says:

    Most definitely YES. I do it all the time when I am sick as each does a different function in you body with different medicines.

  8. Renee says:

    Sudafed, brand name for the generic drug pseudoephedrine, is not an antihistamine. (An antihistamine, such as Benadryl, prevents the body's release of histamine, which When taken together, the. Can I Take Triamterene & Claritin D? Detail:http://www.ehow.com/facts_5318175_sudafed-antihistamine.html

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