Currently there are "8 comments" on this Question:

  1. Jacquetta says:

    What do you do to make you not tired. Sleep is always a good way to combat tiredness but isn't always possible for everyone due to commitments.

  2. Lynne says:

    Benadryl is a antihistamine that does make you tired. However if you take it for long period of time it may decrease this effect.

  3. Earnestine says:

    Does Benadryl allergy/cold make you drowsy like regular Benadryl does? i can take a regular all the way through the benadryl at night and sleep night, which is why i buy it. i

  4. Eden says:

    Benadryl contains the histamine-blocker diphenhydramine which can cause sleepiness or the feeling of being drowsy. More:http://www.chacha.com/question/what-makes-you-tired-that's-in-benadryl

  5. Eve says:

    The ingredient diphenhydramine in Benadryl is what makes you tired. More:http://www.chacha.com/question/what-does-benadryl-make-you-so-tired

  6. Lia says:

    The antihistamine Diphenhydramine, brand name Benadryl, causes drowsiness because it has sedative properties. Thanks! More:http://www.chacha.com/question/how-come-benadryl-makes-people-tired

  7. Kittie says:

    Benadryl is a antihistamine that does make you tired. However if you take it for long period of time it may decrease this effect. Source(s): retired nurse

  8. Nellie says:

    Why Do Antihistamines Make You Tired? Diphenhydramine, known by the brand name Benadryl, helps fight histamine by binding to the receptors of specific Detail:http://www.ehow.com/how-does_5179177_do-antihistamines-make-tired_.html

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