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Currently there are "8 comments" on this Question:

  1. Alethia says:

    Read the label

  2. Tashia says:

    Benadryl contains diphenhydramine hydrochloride, which coincindentally is the ingrediant in Tylenol PM that is the sleep aid. On Tylenol PM, it instructs you to take a half hour before going to sleep……soooooooo….about a half hour. LOLBut really it depends on your body type, metabolism, if youve eaten something….all that stuff.

  3. Lynda says:

    I’m on on effexor 75mg a week now and still feel drowsy. How long will the drowsy effect go on for?

  4. Johnnie says:

    When taking Benadryl for sleep, it’s recommended to take 25-50mg. You should start feeling drowsy within 30 minutes after taking, but a lot depends on the person and their chemistry. More:http://www.chacha.com/question/how-long-does-it-take-for-benedryl-to-make-you-drowsy-and-fall-asleep

  5. Phyliss says:

    Benadryl contains diphenhydramine hydrochloride, which coincindentally is the ingrediant in Tylenol PM that is the sleep aid. On Tylenol PM, it instructs you to take a half hour before going to sleep……soooooooo….about a half hour. LOL… More:http://answers.yahoo.com/question/index?qid=20090505131144AAyBYLv

  6. Consuelo says:

    The first responder has given the correct answer. I’ll just mention the fact that sometimes different people response differently to various medications. What makes one person sleepy may make another person antsy, irritable, and wide awake…. More:http://answers.yahoo.com/question/index?qid=20081214174937AA0uygK

  7. Toni says:

    Benadryl affects each individual differently depending on the dosage and their body chemistry. Most experts recommend to avoid driving or any activities that ability may be impaired by for at least 8 hours.

  8. Kathline says:

    Diphenhydramine, known by the brand name Benadryl, helps fight histamine by binding to the How Long Does It Take for Seroquel to Make One Sleepy? Detail:http://www.ehow.com/how-does_5179177_do-antihistamines-make-tired_.html

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