Currently there are "6 comments" on this Question:

  1. Junita says:

    Jan 10, 2012 Physician reviewed Nyquil Cold Medicine patient information – includes A dangerous drug interaction could occur, leading to serious side effects. Ask a doctor or pharmacist if it is safe for you to take this medicine if you have: . Cold Medicine – CAN YOU TAKE NYQUIL AND BENADRYL TOGETHER?

  2. Janella says:

    Is it safe to mix Benadryl, I would use Nyquil, or I would use Benadryl and Nyquil? Whenever I’ve been having trouble falling asleep instead. But I have a big test 3 days from

  3. Terri says:

    Benadryl (diphenhydrAMINE) and doxylamine (Ingredient of Nyquil Cold & Flu) will have a Moderate Drug-Drug interaction. There are possible health risks. More:

  4. Destiny says:

    It depends on your body weight but be careful about taking too much of either of these. Its not hard to over dose on acetaminophen (common pain killer/fever reducer found in nyquil), and even in normal doses its not great for your body. Thi… More:

  5. Nubia says:

    Are you aware that Nyquil HAS Benadryl in it, in its generic form, therefore you will be double-dosing yourself? My guess is that you should stick with just Nyquil.

  6. Joycelyn says:

    There are some medications approved for use by pregnant woman, but is Nyquil The ingredients in Nyquil that are generally thought to be bad for an unborn baby and ill include Tylenol, Sudafed, Vick's, Robitussin, Hall's and Benadryl. Detail:

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