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Will Benadryl make me tired for hours?

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Yes. The effect of Benadryl (Diphenhydramine) effects usually last 4-6 hours. Side effects are: dry mouth, confusion, dizziness, drowsiness, fatigue, disturbed coordination, irritability, paresthesia, blurred vision, and depression. Any comments?

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Currently there are "8 comments" on this Question:

  1. Claretta says:

    Why does benadryl make you tired? Answer It! Relevant answers: What do you do to make you not tired. Sleep is What will make me tired. Unasame sleep

  2. Brynn says:

    It depends on your bodys normal reaction to Benadryl. If it (or NyQuil, Tylenol PM, etc) make you sleepy at home, theyll make you sleepy on a plane. I wouldnt recommend taking ANY medications to help you try to sleep on a plane if youve not tried them several times at home; some of these meds (especially Ambien, NyQuil, and Claritin) can make some folks nervous, irritable and cause insomnia, and a 15-hour flight is not the time to discover that Benadryl makes you agitated. Try a few different remedies at home; give each a few nights testing and see which works best for you. Also, pay attention to how you feel when you wake up, not just how hard these knock you out, because some can give you a hangover sort of feeling which would be really unpleasant on a plane.

  3. Sherly says:

    Does Benadryl allergy/cold make you drowsy like regular Benadryl does? i can take a regular all the way through the benadryl at night and sleep night, which is why i buy it. i

  4. Clora says:

    Benadryl contains the histamine-blocker diphenhydramine which can cause sleepiness or the feeling of being drowsy. More:http://www.chacha.com/question/what-makes-you-tired-that's-in-benadryl

  5. Vanesa says:

    That all depends on where the nearest Canadian Tire store is located. Since this question is in the Edmonton category, you will have to note that there are actually nine (9) Canadian Tire stores in this city (and one in St. Albert), so whic… More:http://wiki.answers.com/Q/What_are_Canadian_Tire_store_hours

  6. Deloise says:

    The ingredient diphenhydramine in Benadryl is what makes you tired. More:http://www.chacha.com/question/what-does-benadryl-make-you-so-tired

  7. Pa says:

    How long will it take for Benadryl to make me sleepy? not to use to make someone sleepy so be careful and it might take like 1 hour maybe!

  8. Larue says:

    Diphenhydramine, known by the brand name Benadryl, helps fight histamine by binding to the receptors of How Long Does It Take for Seroquel to Make One Sleepy? sleepiness, somnolence and hypersomnia, and is a strong desire to sleep during waking or daytime hours. Are High Triglycerides Making Me Tired ? Detail:http://www.ehow.com/how-does_5179177_do-antihistamines-make-tired_.html

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